Recent Publications

76  "A Turn-On AIE Active Fluorescent Sensor for Hg2+ by combination of 1,1-Bis(2-pyridyl)ethylene and Thiophene/Bithiophene Fragments.” Moustafa T. Gabr and F. Christopher Pigge, Mater. Chem. Front. 2017, 1, 1654-1661.

75  "Synthesis and Evaluation of Tetraarylethylene-based Mono-, Bis-, and Tris(pyridinium) Derivatives for Image-Guided Mitochondria-Specific Targeting and Cytotoxicity of Metastatic Melanoma Cells.” Jessica L. Reedy, Devin K. Hedlund, Moustafa T. Gabr, Grant M. Henning, F. Christopher Pigge, and Michael K. Schultz, Bioconjugate Chem. 2016, 27, 2424-2430.

74  "Construction of 1,2,4-Triazole Derivatives via Cyclocondensation of Alkylidene Dihydropyridines and Aryldiazonium Salts." Madhur S. Joshi and F. Christopher Pigge, Org. Lett. 2016, 18, 5916-5919.

73  “Strain-Promoted Cycloadditions for Development of Copper-Free Click Reactions.” F. Christopher Pigge, Curr. Org. Chem. 201620, 1902-1922.

72  ‘’A Selective Fluorescent Sensor for Zn2+ based on Aggregation-Induced Emission (AIE) Activity and Metal Chelating Ability of Bis(2-pyridyl)diphenylethylene.’’ Moustafa T. Gabr and F. Christopher Pigge, Dalton Trans. 2016, 45, 14039.

71   ‘’Alkylidene Dihydropyridines as Synthetic Intermediates: Model Studies toward the Synthesis of the Bis(piperidine) Alkaloid Xestoproxamine C.’’ Ashabha I. Lansakara, S. V. Santhana Mariappan and F. Christopher Pigge, J. Org. Chem. 2016, 81, 10266-10278.

70  ‘’Dearomatized Alkylidene Dihydropyridines as Substrates for Mizoroki-Heck Cyclizations.’’ Madhur S. Joshi and F. Christopher Pigge, ACS Catalysis. 2016, 6, 4465-4469. 

69  ‘’Synthesis and Aggregated-Induced Emission Properties of Pyridine and Pyridinium Analogues of Tetraphenylethylene.’’ Moustafa T. Gabr and F. Christopher Pigge, RSC Adv. 2015, 5, 90226-90234. 

68  ‘’Charge-Assisted Halogen Bonding in Bromo- and Iodophenylpyridinium Chlorides.’’ Christopher J. Kassl, Dale C. Swenson and F. Christopher Pigge, Cryst. Growth Des. 2015, 15, 4571-4580.

67  "Intramolecular Cyclization of Alkylimidazoles." Madhur S. Joshi, Ashabha I. Lansakara, and F. Christopher Pigge, Tetrahedron Lett. 2015, 56, 3204-3207.

66  “Anion Detection by Aggregation-Induced Enhanced Emission (AIEE) of Urea-Functionalized Tetraphenylethylenes.” Christopher J. Kassl and F. Christopher Pigge, Tetrahedron Lett. 2014, 55, 4810-4813.

65  “Brønsted Acid Catalyzed Intramolecular Benzylic Cyclizations of Alkylpyridines.” Ashabha I. Lansakara, Daniel P. Farrell, and F. Christopher Pigge, Org. Biomol. Chem. 2014, 12, 1090-1099.

64  “Gold-Catalyzed Intramolecular Cyclization of Alkynones with Pyridine Anhydrobases.”  Lokesh Pawar and F. Christopher Pigge, Tetrahedron Lett. 2013, 54, 6067-6070.

63  “Harnessing Aggregation Induced Emission (AIE) of Tetraphenylethylenes in Metal Ion Sensing and Luminescent Metal-Organic Frameworks.” F. Christopher Pigge, J. Mol. Eng. Mater. 2013, 1, 1340009

62  "Halogen Bonded Networks from Pyridyl-Substituted Tetraarylethylenes and Diiodotetrafluorobenzenes.” F. Christopher Pigge, Pradeep P. Kapadia, and Dale C. Swenson, CrystEngComm 2013, 15, 4386-4391.

61  “MRI Markers for MRI-Guided HDR Brachytherapy: Novel Marker-Flange for Cervical Cancer and Marker-Catheters for Prostate Cancer.” Joshua Schindel, Manickam Muruganandham,  F. Christopher Pigge, James Anderson, and Yusung Kim, Int. J. Radiation Oncol. Biol. Phys. 2013, 86, 387-393.

60  “Intramolecular Cyclization Manifolds of 4-Alkylpyridines Bearing Ambiphilic Side Chains: Construction of Spirodihydropyridines or Benzylic Cyclization via Anhydrobase Intermediates.” Sharavathi G. Parameswarappa and F. Christopher Pigge, J. Org. Chem. 2012, 77, 8038-8048.

59  “Influence of Halogen Bonding Interactions in Crystalline Networks of Tetraarylethylene Halobenzoyl Esters.” Pradeep P. Kapadia, Dale C. Swenson, and F. Christopher Pigge, Cryst. Growth Des. 2012, 12, 698-706.

58  “Improved Synthesis and Biological Evaluation of Chelator-Modified a-MSH Analogues Prepared by Copper-Free Click Chemistry.” Nicholas J. Baumhover, Molly E. Martin, Sharavathi G. Parameswarappa, Kyle C. Kloepping, M. Sue O’Dorisio, F. Christopher Pigge, and Michael K. Schultz, Bioorg. Med. Chem. Lett. 2011, 21, 5757-5761.

57  “Generation and Solid State Characterization of Tetrapyridinium Perchlorate Salts Derived from Tetrapyridyl Tetraphenylethylenes.” Pradeep P. Kapadia, Mackenzie A. Magnus, Dale C. Swenson, and F. Christopher Pigge, J. Mol. Struct. 2011, 1003, 82-86. 

56  “Synthesis of Substituted 3,9-Diazaspiro[5.5]undecanes via Spirocyclization of Pyridine Substrates.” Sharavathi G. Parameswarappa and F. Christopher Pigge, Tetrahedron Lett. 2011, 52, 4357-4359.

55  “Semiconducting Organic Assemblies Prepared from Tetraphenylethylene Tetracarboxylic Acid and Bis(pyridine)s via Charge-Assisted Hydrogen Bonding.” Pradeep P. Kapadia, Lindsay R. Ditzler, Jonas Baltrusaitis, Dale C. Swenson, Alexei V. Tivanski, and F. Christopher Pigge, J. Am. Chem. Soc. 2011, 133, 8490-8493.

54  “Tetrapyridyl Tetraphenylethylenes: Supramolecular Building Blocks with Aggregation Induced Emission Properties.” Pradeep P. Kapadia, John C. Widen, Mackenzie A. Magnus, Dale C. Swenson, and F. Christopher Pigge, Tetrahedron Lett. 2011, 52, 2519-2522.

53  “Losing Control? “Design” of Crystalline Organic and Metal-Organic Networks using Conformationally Flexible Building Blocks.” F. Christopher Pigge, CrystEngComm 2011, 13, 1733-1748.  [Invited review]

52  “Titanium-Mediated Spirocyclization Reactions of 4-Alkyl Pyridines.” Sharavathi G. Parameswarappa and F. Christopher Pigge, Org. Lett. 2010, 12, 3434-3437.

51  “A DOTA-Peptide Conjugate by Copper-Free Click Chemistry.” Molly E. Martin, Sharavathi G. Parameswarappa, M. Sue O’Dorisio, F. Christopher Pigge, and Michael K. Schultz, Bioorg. Med. Chem. Lett. 2010, 20, 4805-4807.

50  “Synthesis of a DOTA-Biotin Conjugate for Radionuclide Chelation via Cu-Free Click Chemistry.” Michael K. Schultz, Sharavathi G. Parameswarappa, and F. Christopher Pigge, Org. Lett. 2010, 12, 2398-2401.

49  “Metal Catalyzed Allylation of Organoboranes and Organoboronic Acids.”  F. Christopher Pigge, Synthesis 2010, 1745-1762.  [Invited review]

48  “Examination of Halogen Bonding Interactions in Electronically Distinct but Structurally Related Tris(haloarenes).”  F. Christopher Pigge, Venu R. Vangala, Dale C. Swenson, and Nigam P. Rath, Cryst. Growth Des. 2010, 10, 224-231.

47  “Synthesis of Polycyclic Cyclohexadienyl Ruthenium(II) Complexes from h6-Arene Precursors via Phosphine Promoted Intramolecular Nucleophilic Aromatic Addition.” F. Christopher Pigge, R. Dhanya, and Dale C. Swenson, Organometallics 2009, 28, 3869-3875.

46  “A 1D Crystalline Organic Polyrotaxane Formed via Hydrogen Bond-Mediated Self-Assembly of a Conformationally Flexible Tri-Carboxylic Acid.” F. Christopher Pigge, Mayuri K. Dighe, and Dale C. Swenson, CrystEngComm 2009, 11, 1227-1230.

45  “Metal-Mediated Dearomatization Leading to 2-Azaspiro[4.5]decanes via Tandem Nucleophilic Aromatic Addition – Horner-Wadsworth-Emmons Olefination – Oxidative Demetalation Sequences.” F. Christopher Pigge and Rashmi Dalvi, Tetrahedron 2008, 64, 10123-10131.

44  “Hexagonal Crystalline Inclusion Complexes of 4-Iodophenoxy Trimesoate.” F. Christopher Pigge, Venu R. Vangala, Pradeep P. Kapadia, Dale C. Swenson, and Nigam P. Rath, Chem. Commun. 2008, 4726-4728.

43  “Effect of Remote Substituents on Solid State Packing Interactions in Macrocyclic Crownophanes Derived from 1,3,5-Triaroylbenzenes.” F. Christopher Pigge, Angela V. Schmitt, and Nigam P. Rath, J. Inclusion Phenom. Macrocycl. Chem. 2008, 62, 105-110.

42  “Mono-, Bis-, and Tris(crown ether)s Assembled Around 1,3,5-Triaroylbenzene Scaffolds.” F. Christopher Pigge, Mayuri K. Dighe, and Jon C. D. Houtman, J. Org. Chem. 2008, 73, 2760-2767.

41  “Monolayers of Triaroylbenzene Derivatives.” Mayuri K. Dighe, Frank J. Dover, Keith J. Stine, and F. Christopher Pigge, Thin Solid Films 2008, 516, 3227-3238.