New Approaches to Synthetic Heparin, Other Complex Carbohydrates and 18F-Fluorinated Molecules for PET Imaging via Transition Metal Catalysis.

Nguyen Group - 2016

 

Group Members Spring 2016


Group News

05/2016: Congratulations to Michael Vinyard who will head to graduate school in the fall at Harvard University.

05/2016: Dr. Qi Zhang is the recipient of the 2016 Lynn Anderson Research Excellence Award. This award is given annually in the department for "outstanding Ph.D. work".

04/2016: Congratulations to Qi Zhang for successfully defending his Ph.D. thesis. Best of luck with your new adventure, Dr. Zhang!

04/2016: Congratulations to Jason Mixdorf for receiving NSF Honorable Mention.

01/2016: The Nguyen Lab receives an Innovation Grant from the Mizutani Foundation for Glycoscience to support the carbohydrate adjuvant project.

12/2015: Welcome first year graduate students, Jalen Dickson and Alex Sorlin, to our research group!

11/2015: Our group paper, "Studies of Highly-Ordered Heterodiantennary Mannose/Glucose-Functionalized Polymers and Concanavalin A Protein Interactions Using Isothermal Titration Calorimetry" has been accepted for publication in Biomacromolecules. Congratulations to Ravi and Matt!

09/2015: Our group paper, "Iridium-Catalyzed Enantioselective Fluorination of Racemic, Secondary Allylic Trichloroacetimidates" has been published on ASAP in JACS. Congratulations to everyone on this project!

07/2015: Congratulations to Matt McConnell for successfully defending his Ph.D. thesis. Best of luck with your new adventure, Dr. McConnell!

06/2015: Matthew McConnell, a current graduate student, will start his postdoctoral position at Northwestern University after he defends in July, 2015. Congratulations, Matt!

06/2015: Matthew McKay, a former graduate student, started his new position as a Senior Patent Agent at Cabot Microelectronics in Chicago. Congratulations, Matt!

06/2015: Joseph Topczewski, a former visiting student/postdoctoral fellow, will start his independent career as an Assistant Professor at University of Minnesota this summer. Congratulations, Joe!

05/2015: Congratulations Michael Vinyard for receiving the ACS Travel Award to attend the National Organic Symposium in Maryland.

05/2015: Congratulations to Riley Svec who will head to graduate school in the fall at University of Illinois at Urbana-Champaign.

05/2015: Our invited paper for Professor Barry Trost's Tetrahedron Award, "Rhodium-Catalyzed Benzylic Fluorination of Trichloroacetimidates" has been published. Congratulations, Qi, Jason, and Gil!

05/2015: Jason Mixdorf officially becomes the first year graduate student in our research group!

04/2015: Fei and Matt's paper, "Scalable Synthesis of Fmoc-Protected GalNAc-Threonine Amino Acid and Tn Antigen via Nickel Catalysis" has been published on ASAP in Organic Letters. Congratulations, Fei and Matt!

02/2015: We are notified that we will receive the Carver Collaborative grant entitled, "Zwitterionic Carbohydrate Adjuvants". This project will be performed in collaboration with Professor Steve Varga in the Department of Microbiology here at Carver College of Medicine.

02/2015: Eric and Riley's paper, "Synthesis of a polymerizable, bivalent glycan mimetic of the HIV envelope spike gp120," has been accepted for publication by Tetrahedron Letters to dedicate in memory of Professor Harry Wasserman at Yale. Congratulations, Eric and Riley!

12/2014: Four first year graduate students, Alisa Fairweather, Anh Lu, Binbin Lin, and Gil Reynders, have joined our research group. Welcome to the lab!

05/16/2014: Congratulations to Jeff Arnold and Matt McKay for receiving their Ph.D. degree. Best of luck with your new adventure, Dr. Arnold and Dr. McKay!

04/2014: Enoch Mensah, a former graduate student, will start his independent career as an Assistant Professor at Indiana University Southeast in July, 2014. Congratulations, Enoch!

04/2014: Jeff Arnold successfully defended his Ph.D. thesis, Congratulations, Dr. Arnold! Jeff finished up with 7 publications and his thesis is longer than 700 pages. Best of luck with your new position at Corden Pharm.

04/2014: Riley Svec, our undergraduate student, has been selected to receive the ACS Division of Organic Chemistry Undergraduate Summer Research Fellowship (SURF). Congratulations, Riley!

04/2014: Jeff Arnold and Qi Zhang's Review paper - Transition-Metal-Catalyzed Allylic Substitutions of Trichloroacetimidates - has been accepted to European Journal of Organic Chemistry. Congratulations, Jeff and Qi!

03/2014: Matt McKay and Nathan Park's paper - Investigations of Scope and Mechanism of Nickel-Catalyzed Transformation of Glycosyl Trichloroacetimidates to Glycosyl Trichloroacetamides and Subsequent, Atom-Economical, One-Step Conversion to alpha-Urea-Glycosides - has been accepted to Chemistry - A European Journal. Congratulations, Matt and Nathan!

02/2014: Jeff Arnold and Edo Mwenda's paper - Rhodium-Catalyzed Enantioselective Synthesis of Seven-Membered Nitrogen Heterocycles - has been accepted to Angewadte Chemie and selected as a "HOT PAPER." Congratulations, Jeff and Edo!

01/2014: Hien was invited as a speaker at Advances in Glycochemistry Symposium at IIT, Bombay, India

01/2014: Hien was invited as a speaker at Frontiers in Chemistry and Biology of Oligosaccharide at Indian Institute of Science Education and Research, Pune, India

01/2014: Hien was invited as a speaker at the 27th International Carbohydrate Symposium in Bangalore, India

01/2014: Matt McKay's review article - Recent Development in Glycosyl Urea Synthesis - has been published in Carbohydrate Research, 2014, 385, 18-44. Congratulations, Matt!

12/2013: Eric Sletten, a first year graduate student, joined our research group.

12/2013: Matt McKay successfully defended his Ph.D. thesis, Congratulations, Matt! Best of luck with your adventure at Northwestern Law School.

09/2013: Qi Zhang's paper - Rhodium-catalyzed regioselective ring opening of vinyl epoxides with HF-TEA - formation of allylic fluorohydrins - has been just accepted to Chemical Science. Congratulations, Qi!

09/2013: Matt McConnell's paper - Stereoselective alpha-glycosylation of C(6)-hydroxyl myo-inositols via nickel catalyssis-application to the synthesis of GPI anchor pseudo-oligosaccharides - has been recently accepted to Carbohydrate Research. Congratulations, Matt!

08/2013:  Matt McKay's review article - Recent Developments in alpha-Urea Glycoside Synthesis - has recently published in Carbohydrate Research. This article is invited for special issue on International Young Carbohydrate Investigators Symposium which took place in Madrid, Spain in July, 2012.

07/2013: Jeff Arnold's paper - Rhodium-Catalyzed Asymmetric Amination of Allylic Trichloroacetimidates - has recently been published in Synthesis, 2013, 45, 2101-2108. This article is invited for special issue on rhodium catalysis.  Congratulations, Jeff!

05/2013: Congratulations to both Kathleen and Drew! Kathleen and Drew will head to graduate school in the Fall - Kathleen will be at MIT and Drew at University of Pennsylvania.

03/2013: Kathleen White has been awarded NSF graduate fellowship.  Congratulations, Kathleen!

03/2013: Hien was selected as Dean's Scholar from among those faculty recommended for promotion and/or tenure by the College of Arts and Sciences Committee on Faculty Promotion and Tenure

03/2013: Matt McConnell and Qi Zhang were awarded Summer Graduate Research Fellowship.

12/2012: Hien was named 2013 Thieme Journal Chemistry Awardee

12/2012: Edo Mwenda, Dibyendu Mondal and Sulay, first year graduate students, joined our lab.

10/2012: Kathleen has been selected as the McKnight Finalist.  She will present her work at the University of Texas Southwestern Medical Center in November.

10/2012: Jeff, Greg, and Drew's paper - Rhodium-Catalyzed Regioselective and Enantioselective Amination of Racemic Secondary Allylic Trichloroacetimidates with Acyclic N-Methyl Anilines- has been accepted to Chemical Communication(DOI: 10.1039/c2cc36961c).

09/2012: Fei Yu and Matt McConnell's paper-Nickel-Catalyzed alpha-Glycosylation of C(1)-Hydroxyl Group of Inositol Acceptors: A Formal Synthesis of Mycothiol- has been accepted to Chemical Communication (DOI: 10.1039/c2cc35823a). This article was invited for the 2013 Emerging Investigator Issue.

09/2012: Dr. Fei Yu's paper- Studies on the Selectivity Between Nickel-Catalyzed 1,2-Cis-2-Amino Glycosylation of Hydroxyl Groups of Thioglycoside Acceptors with C(2)-Substituted Benzylidene N-Phenyl Trifluoroacetimidates and Intermolecular Aglycon Transfer of the Sulfide Group- has recently been published in Journal of Organic Chemistry, 2012, 77, 7330-7343.

07/2012: Matt McKay's review article- Recent Advances in Transition Metal-Catalyzed Glycosylation- has been published in ACS Catalysis, 2012,2, 1563-1595.

07/2012: Jeff's JACS paper (2012,134, 8380)- Rhodium-Catalyzed Dynamic Kinetic Transformations of Racemic Tertiary Allylic Trichloroacetimidates with Anilines- was highlighter in SYNFACT, 2012, 8, 862.

05/2012: Our manuscript on Rhodium-Catalyzed Dynamic Kinetic Asymmetric Transformations of Racemic Tertiary Allylic Trichloroacetimidates with Anilines has recently been published in JACS (ASAP, 05/14/2012, DOI: ja302223p). Congratulations to Jeff!

05/2012: All of our undergraduate students received the Department of Chemistry Awards.

  • Nate Oldenhuis – Chemistry Alumni Award
  • Gregory Cizio – Ken Sando Scholarship and Third Place Poster Presentation
  • Kathleen White – Russell K. Simms Scholarship
  • Drew Heitz – Donald and Margaret Burton Organic Scholarship

04/2012: Qi Zhang and Matt McConnell pass the Comprehensive Exams and advance to the Ph.D. candidacy. Well done!

04/2012: Drew Heitz, our undergraduate student, receives a SURF award from the ACS. Congratulations Drew!

04/2012: Nate Oldenhuis, our undergraduate student, receives Honorable Mention from an NSF Graduate Research Fellowship. Great job, Nate!

03/2012: Kathleen White, one of our undergraduate students, receives an Amgen Summer Fellowship at MIT. Kathleen will spend the summer in the lab of Tim Swager. Congratulations, Kathleen!

02/2012: Hien was invited to give a presentation at the Carbohydrate Young Investigator Symposium at the International Carbohydrate Meeting in Madrid, Spain in July

11/2011: Congratulations to Enoch Mensah for getting his Ph.D. He will start his postdoctoral position at the University of Michigan in January, 2012.

11/2011: Our manuscript on Iridium-Catalyzed Regioselective Fluorination of Allylic Trichloroacetimidates has been published in JACS (ASAP, 11/11/2011, DOI: ja2087213). Congratulations to Joe.

10/2011: Our paper on Rhodium-Catalyzed Regioselective Amination of Tertiary Allylic Trichloroacetimidates has been published in Organic Letters, 2011, 13, 5576. Congratulations to Jeff and Greg.

04/2011:  Enoch, Jeff, and Matt received Graduate College Summer Fellowship.

02/2011:  Hien was invited to give a presentation at Organic Assistant Professors Symposium at the Fall ACS Meeting in Denver

01/2011:  Hien was invited to give a presentation at the Carbohydrate Gordon Conference

  • Alexandre, Alisa, and Eric finished the 10K Chicago Marathon

    Alexandre, Alisa, and Eric finished the 10K Chicago Marathon

  • A day in the life Group 2016

    A day in the life Group 2016

  • Nguyen Group - 2016

    Nguyen Group - 2016

  • Nguyen Group - 2009

    Nguyen Group - 2009

  • Nguyen Group - 2008

    Nguyen Group - 2008

  • Enoch Mensah - Our First Ph.D. Graduate Student

    Enoch Mensah - Our First Ph.D. Graduate Student

  • Enoch Graduation - December, 2011

    Enoch Graduation - December, 2011

  • Joe T was excited with his fluorination results

    Joe T was excited with his fluorination results

  • Matt McKay was working and listening to music at the same time

    Matt McKay was working and listening to music at the same time

  • ACS Meeting - San Francisco, March, 2010

    ACS Meeting - San Francisco, March, 2010